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温肾泄浊汤联合西药治疗慢性肾功能衰竭随机平行对照研究 被引量:4

Wenshen Xiezhuo Method Combined with Western Medicine in the Treatment of Chronic Renal Failure Randomized Controlled Study
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摘要 [目的]观察温肾泄浊汤加减联合西药治疗慢性肾功能衰竭疗效。[方法]使用随机平行对照方法,将68例门诊患者按随机数字表法随机分为两组。对照组34例,采用西医常规治疗,低盐、低脂、优质低蛋白饮食控制感染、控制血压、抗贫血及止血、纤正水、电解质酸碱平衡失调等对症治疗。阿魏酸钠0.3g/次,1次/d,静滴。治疗组34例,方选温肾泄浊汤加减治疗,药用制附子5g,党参15g,白术15g,茯苓15g,黄芪25g,川芎10g,山茱萸15g,山药20g,仙灵脾15g,石韦15g,陈皮10g,大黄15g,甘草10g,金樱子15g,1剂/d,水煎200mL,早晚口服。西药治疗同对照组。连续治疗90d为1疗程。观测临床症状、生化指标、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组显效14例,有效16例,无效4例,总有效率88.23%。对照组显效8例,有效14例,无效12例,总有效率64.71%。治疗组疗效优于对照组(P<0.05)。治疗前后续生化指标治疗组治疗组优于对照组(P<0.05)。[结论]温肾泄浊汤加减联合西药治疗慢性肾功能衰竭,疗效满意且不增加副作用。 [ Objective ] To observe Wenshen Xiezhuo decoction combined with Western medicine treatment of chronic renal failure efficacy. [ Method] Use randomized controlled method, 68 outpatients were randomly divided into two groups by random number table. The control group of 34 patients using conventional Western medicine treatment, low - salt, low - fat, high - quality low - protein diet, infection control, blood pressure control, resistant anemia and hemostasis, the symptomatic treatment of the fiber being water, electrolyte and acid - base balance disorders. With sodimn fernlate 0.3g once every day, intravenous infusion. The treatment group, 34 patients the square- election Wenshen Xiezhuo decoction treatment, use Fuzi 5g, Dangshen 15g, Baizhu 15g, Fuling 15g, Huangqi 25g, Chuanxiong 10g, Shanzhuyu 15g, Shanyao 20g, Xianlingpi 15g, Shi- wei 15g, Chenpi 10g, Dahuang 15g, Gancao 10g, Jinyingzi 15g, 1 dose every day, decoction 200mL, oral sooner or later. Western medicine with the control group. Continuous treatment for 90 days to 1 course of lreatment. Observation of clinical symptoms, biochemical markers and adverse reactions. Continuous treatment of a course of treatment to determine efficacy. [Results] Treatment group, 14 cases were markedly effective, 16 cases were effective, 4 case were invalid, the total efficiency of 88.23%. Control group, 8 cases were markedly effective, 14 cases were effective, 12 cases were invalid, the total effective rate of 64.71%. The clinical efficacy of the treatment group than the control group (P 〈 0.05 ). Treatment before the follow - up the biochemical indicators treatment group treatment group than the control group (P 〈 0.05 ). [ Conclusion ] Warming Xiezhuo decoction combined with Western medicine treatment of chronic renal failure, a satisfactory outcome without increasing side effects.
出处 《实用中医内科杂志》 2013年第2期20-22,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 慢性肾功能衰竭 温肾泄浊汤 阿魏酸钠 随机平行对照研究 Chronic renal failure Wenshen Xiezhuo method Wenshen Xiezhuo decoction Western medicine Randomized controlled study
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