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左西替利嗪治疗荨麻疹的临床观察 被引量:4

Clinical observation on levocetirizine for treatment of urticaria
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摘要 目的观察左西替利嗪治疗荨麻疹的临床疗效及安全性。方法 78例荨麻疹患者(其中急性荨麻疹41例,慢性荨麻疹37例)接受左西替利嗪(5mg/片),1次1片,每天1次,进行治疗效果和安全性的评价。结果急性荨麻疹的有效率为92.7%,慢性荨麻疹有效率为75.7%,总有效率为84.6%,总不良反应率为5.1%。结论左西替利嗪治疗荨麻疹是安全且有效。 Objective To observe the clinical efficacy and safety of levocetirizine in the treatment of urticaria patients. Methods 78 patients(41 cases of acute urticarial patients and 37 case of chronic urticarial patients) received levocetirizine(5mg/table),one tablets each time,once a day,and evaluated the efficacy and safety. Results The effective rate of acute urticaria patients was 92.7% and 75.7% in chronic urticaria.The total effective rate was 84.6%,and the total rate of the side effect was 5.1%. Conclusions Levocetirizine is effective and safe for the treatment of urticaria.
作者 韩洪方 曹慧
出处 《齐齐哈尔医学院学报》 2013年第8期1136-1137,共2页 Journal of Qiqihar Medical University
关键词 左西替利嗪 荨麻疹 临床疗效 Levocetirizine Urticaria Clinical efficacy
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参考文献10

  • 1Frossard N, Strolin-Benedetti M, Purohit A, et al. Inhibition of allergen-induced wheal and flare reactions by levocetirizine and desloratadine. Br J Clin Pharmacol,2008,65 (2) : 172-179.
  • 2Fang SY, Perng DW, Lee JY, et al. An open-label, muhicentre study of levocetirizine for the treatment of allergic rhinitis and urticaria in Taiwan Residents patients. Chin J Physio1,2010,53 (4) : 199- 207.
  • 3Bousquet J, Demarteau N, Mullol J, et al. Costs associated with persistent allergic rhinitis are reduced by levocetirizine. Allergy, 2005,60 (6) :788-794.
  • 4沈辉,刘海琴.左旋西替利嗪治疗慢性荨麻疹疗效观察[J].临床皮肤科杂志,2006,35(5):330-331. 被引量:33
  • 5Gaig P, Olona M, Mufioz Lejarazu D, et al. Epidemiology of urticaria in Spain. J Investig Allergol C lin Immunol,2004,14 (3) : 214-220.
  • 6Sidbury R, Hanifin JM. Systemic therapy of atopic dermatitis. Clin Exp Dermatol,2000,25 (7) :559-566.
  • 7郝飞,李惠,鲁元刚,尹锐,陈家秀,伍津津,孙仁山,邓军.左西替利嗪与西替利嗪治疗慢性荨麻疹多中心随机双盲对照研究[J].中华皮肤科杂志,2004,37(6):320-322. 被引量:53
  • 8全小荣.左西替利嗪治疗慢性荨麻疹疗效观察[J].中国皮肤性病学杂志,2005,19(11):702-703. 被引量:27
  • 9Potter PC, Kapp A, Maurer M, et al. Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients. Allergy,2009,64(4) :596-604.
  • 10Augustin M, Ehrle S. Safety and efficacy of desloratadine in chronic idiopathic urticaria in clinical practice: an observational study of 9246 patients. J Eur Acad Dermatol Venereol, 2009,23 ( 3 ) : 292- 299.

二级参考文献15

  • 1郝飞,李惠,鲁元刚,尹锐,陈家秀,伍津津,孙仁山,邓军.左西替利嗪与西替利嗪治疗慢性荨麻疹多中心随机双盲对照研究[J].中华皮肤科杂志,2004,37(6):320-322. 被引量:53
  • 2尹锐,郝飞,向明明,孙仁山,邓军.盐酸左西替利嗪治疗慢性特发性荨麻疹的临床研究[J].临床皮肤科杂志,2003,32(8):477-478. 被引量:22
  • 3梁华平,张艳,耿波.黄芪多糖对烧伤小鼠细胞免疫功能的影响[J].中华整形烧伤外科杂志,1994,10(2):138-141. 被引量:93
  • 4Gillard M,Van der Perren C,Massingham R,et al.Binding characteristics of [3H]levocetirizine to cloned human H1-histamine-receptors expressed in CHO cells.Inflamm Res,2002,51 Suppl 1:S77-S78.
  • 5Devalia JL,De Vos C,Hanotte F,et al.A randomized,doubleblind,crossover comparison among cetirizine,levocetirizine,and ucb 28557 on histamine-induced cutaneous responses in healthy adult volunteers.Allergy,2001,56:50-57.
  • 6Wang DY,Hanotte F,De Vos C,et al.Effect of cetirizine,levocetirizine,and dextrocetirizine on histamine-induced nasal response in healthy adult volunteers.Allergy,2001,56:339-343.
  • 7Clough GF,Boutsiouki P,Church MK.et al.Comparison of the effects of levocetirizine and loratadine on histamine-induced wheal,flare,and itch in human skin.Allergy,2001,56:985-988.
  • 8Thomson L,Blaylock MG,Sexton DW,et al.Cetirizine and levocetirizine inhibit eotaxin-induced eosinophil transendothelial migration through human dermal or lung microvascular endothelial cells.Clin Exp Allergy,2002,32:1187-1192.
  • 9Leynadier F,Mees K,Arendt C,et al.Efficacy and safety of levocetirizine in seasonal allergic rhinitis.Acta Otorhinolaryngnl Belg,2001,55:305-312.
  • 10Baltes E,Coupez R,Giezek H,et al.Absorption and disposition of levocetirizine,the eutomer of cetirizine,administered alone or as cetirizine to healthy volunteers.Fundam Clin Pharmacol,2001,15:269-277.

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