伴有脑梗死的偏头痛临床特征分析

Correlation of ischemic stroke and migraine

目的分析伴有脑梗死的偏头痛的临床特征。方法收集我院2009-01至2012-10收治的年龄为20～40岁的青年偏头痛298例,其中合并脑梗死39例(A组),随机选取无脑梗死偏头痛患者39例(B组),对两组的一般资料、临床症状进行对比分析。结果两组间在性别、偏头痛病程、头痛发作频率、头痛持续时间、有无先兆、是否口服避孕药方面存在统计学差异(P<0.05);在头痛是否伴有恶心呕吐及偏头痛家族史方面无统计学差异(P>0.05);A组中梗死部位位于大脑后动脉供血区的有26例。结论与无梗死偏头痛患者相比,合并脑梗死的偏头痛患者临床上多伴有先兆症状、头痛病程长、发作更频繁、单次持续时间长,同时伴有高比率的口服避孕药史且梗死部位以大脑后动脉供血区更多见。

Objective To investigate the clinical characteristics of migraine with cerebral infarction. Methods Thirty-nine patients with cerebral infarction were recruited from 298 young patients with migraine（20-40 years）as group A in the People’s Armed Police Forces Hospital from January 2009 to October 2012.And 39 patients without cerebral infarction were randomly recruited from those 298 patients as group B.And in them all, the stroke risk factors were eliminated,including hypertension,diabetes mellitus,atherosclerosis,smoking and history of family hereditary stroke.Then we retrospectively analyzed the general information and clinical symptoms in the two groups.Results Gender,course of migraine disease,frequency of headache,lasting time of headache every time,sign,and contraceptives showed statistically significant difference（P〈0.05）,but nausea and vomiting and family history of migraine were not statistically different in the two groups（P〈0.05）.Twenty-six patients were subjected to infarction in the posterior cerebral artery in the group of 39 patients with cerebral infarction.Conclusions The clinical symptoms and signs in patients with migraine complicated by cerebral infarction consist of long course of headache, more frequent,long lasting in one time,and with a high rate of contraceptive history.Patients with infarction in the posterior cerebral artery are frequently seen.