健脾补肾方治疗肝硬化并发肝肾综合征临床观察

Clinical Observation of Invigorating Spleen and Tonifying Stomach Decoction Treating Cirrhosis Complicated with Hepatorenal Syndrome

目的观察健脾补肾方治疗肝硬化并发肝肾综合征的临床疗效。方法将50例肝硬化并发肝肾综合征患者随机分为治疗组和对照组。对照组25例,常规予保肝、利尿、对症支持、补充白蛋白等治疗。治疗组25例在对照组治疗基础上予自拟健脾补肾方口服。两组患者均以治疗3周为一疗程。1疗程后观察比较两组治疗前后临床症状、腹围、肝肾功能及尿量变化。结果临床疗效比较,治疗组总有效率86.21%,对照组总有效率67.86%。结论健脾补肾方能改善患者临床症状及肝、肾功能,减少腹水形成,延缓病情进展。

Objective To observe the clinical curative effect of Invigorating Spleen and Tonifying Stomach Decoction on treating liver cirrhosis complicated with hepatorenal syndrome. Method 50 patients with liver cirrhosis complicated with hepatorenal syndrome were randomly divided into the treatment group and the control group. A control group of 25 cases, treated with hepatoprotective, diuretic, symptomatic and supportive, complementing albumin treatments. The treatment group of 25 cases based on the treatment in control group were treated by Invigorating Spleen and Tonifying Stomach Decoction. Two groups were treated for 3 weeks as a course of treatment. To observe the changes of clinical symptoms, abdominal circumference, liver and renal function and urine volume , compared them before and after treatment in the two groups after 1 courses of treatment. Results Compared the clinical curative effects, the total effective rate of treatment group was 86.21%, in control group, the total efficiency was 67.86 %. Conclusion Invigorating Spleen and Tonifying Stomach Decoction can improve the clinical symptoms , liver and kidney function, reduce the ascites formation, and delay the progress of the disease.