凯时联合舒血宁治疗突发性耳聋的疗效观察

Synergic Effect of Alprostadil Injection and Shuxuening in Treating Sudden Deafness

目的探讨凯时联合舒血宁治疗突发性聋的疗效。方法对95例(98耳)突发性耳聋患者随机抽样分组,分为甲组(舒血宁组)、乙组(凯时组)、丙组(凯时+舒血宁组),分别给予舒血宁、凯时、凯时联合舒血宁静滴。结果甲、乙、丙组总有效率分别为58.82%、58.06%、87.88%,甲、丙组间及乙、丙组间疗效均差异有统计学意义(均P<0.05),甲、乙组间疗效差异无统计学意义(P>0.05)。纯音电测听听力图中盆型、上升型、平坦型听力图预后较好,下降型及全聋型预后较差。结论凯时及舒血宁治疗突发性聋有效,凯时联合舒血宁治疗突发性聋效果更好,有显著的协同效应。

Object i ve To explore synergic effect of alprostadil injection and shuxuening in treating sudden deafness.Method ninty- five patients （ninty-eight eares） with deafness were divided into group A,B and C at random;patients of group A were treated with shuxuening injection by vein,patients of group B were treated with alprostadil injection by vein,patients of group C were treated with alprostadil injection and shuxuening by vein.Resu 1 t： The effective rate of group A is 58.82%,the effective rate of group B is 58.06%,the effective rate of group C is 87.88%,the treating effect was significantly different in group A and C（-P 〈 0.05）,it was significantly different in group B and C,but also there is no significant difference between group A and B.Conclusion It is effective for alprostadil injection and shuxuening in treating sudden deafness,and it has significantly synergic effect in treating sudden deafness with alprostadil injection and shuxuening.