改良腭咽成形术治疗阻塞性睡眠呼吸暂停综合征的临床疗效对比

The contrast of the clinical effect for uvulopalatopharyngoplasty in the treatment of obstructive sleep apnea hyperpnoea syndrome

目的探讨改良腭咽成形术(H-UPPP)治疗阻塞性睡眠呼吸暂停综合征(OSAS)的临床疗效。方法选取1993年12月～2005年12月采用传统悬雍垂腭咽成形术(UPPP)治疗OSAS患者78例为对照组。按1:1比例选取2006年1月～2012年1月采取改良悬雍垂腭咽成形术(H-UPPP)治疗OSAS患者78例为观察组,随访1年观察两组患者的临床疗效及术后并发症。结果两组患者术后自觉症状均有明显改善,但观察组改善较对照组更为显著。术后1年经多导睡眠呼吸监测(PsG),对照组总临床有效率和并发症的发生率均低于观察组,差异有统计学意义(P<0.05)。结论 H-UPPP通过保留悬雍垂,保留咽腔基本结构,提高了手术疗效,降低了并发症,是治疗OSAS的有效方法。

Objective To investigate the clinical effect for uvulopalatopharyngoplasty （H-UPPP） in the treatment of obstructive sleep apnea hyperpnoea syndrome （OSAS）. Methods Seventy eight cases of patients with OSAS from De- cember 1993 to December 2005 by traditional uvulopalatopharyngoplasty （UPPP） were chosen as the control group. According to the proportion of 1：1 from January 2006 to January 2012, 78 cases with the modified uvulopalatopharyn- goplasty （H-UPPP） in patients with OSAS for treatment were chosen as the observation group. The clinical efficacy and postoperative complications of two groups of patients 1 year of follow-up was taken for observation. Results The postoperative symptoms were obviously improved for the two groups of patients after treatment, but the treatment group improved more significantly than that of the control group. After 1 year of polysomnography （PsG）, the total clinical ef- ficiency and the incidence of complications in the control group was lower than those in the observation group, P 〈 0.05, there was significant difference. Conclusion H-UPPP by reserving uvula pharyngeal cavity, retains the basic structure, improves the operation effect, reduces complications, and it is an effective method in the treatment of OSAS.