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降钙素原在非中性粒细胞减少肿瘤发热患者中的应用研究 被引量:4

Clinical application of procalcitoniniu febrile nou-neutropenic cancer patients
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摘要 目的探讨降钙素原在非中性粒细胞减少肿瘤发热患者中的应用。方法选取本院2010年1月~2012年1月160例非中性粒细胞减少的肿瘤发热患者,在发热1d内和之后3d分别测定血浆降钙素原水平,将患者分为脓毒血症组31例、局部感染组34例、无明确微生物感染组45例和肿瘤相关组50例,比较这些患者的血浆降钙素原水平。结果局部感染组、无明确微生物感染组和脓毒血症组在3d后降钙素原(PCT)明显有下降,而肿瘤组的PCT水平差异无可比性。同时脓毒血症组的PCT水平明显高于其他3组。结论血浆降钙素原水平可用于判断非中性粒细胞减少肿瘤患者发热的具体原因。 Objective To explore procalcitonin in neutrophils reduce tumor fever patients. Methods One hundred and sixty cases with febrile non-ncutrophil cancer patients in the last two years of our hospital were selected. Plasma PCT was measured within one day when fever happened and 3 days later. The patients were divided into sepsis group (31 cases), local infection group (34 cases), 45 cases of non-microbial no clear infection group (45 cases) and tumor- associated group (50 cases). These patients with PCT levels were compared. Results PCT levels of group of local no clear infection, microbial infection and sepsis were dropped at 3 days. PCT levels of tumor-associated group were not changed. And the PCT levels of sepsis group were significantly higher than the other three groups. Conclusion Plasma procalcitonin levels can be used to determine the specific reasons not neutropenic fever in patients with tumors.
作者 陆粤就 陆森
出处 《中国当代医药》 2013年第15期51-52,共2页 China Modern Medicine
关键词 肿瘤发热 非中性粒细胞减少 降钙素原 应用研究 Tumor fever Non neutropenia Procalcitonin Clinical application
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