米非司酮配合乳酸依沙吖啶应用于中孕引产的临床观察

Clinical observation of mifepristone combined with rivanol used in mildtem pregnancy induced labor

目的探讨米非司酮配合乳酸依沙吖啶应用于中孕引产的安全性和有效性。方法将中期妊娠要求引产的健康孕妇分成两组,对照组:羊膜腔内注射乳酸依沙吖啶100mg;试验组:加米非司酮片150mg口服。结果米非司酮配合乳酸依沙吖啶引产的孕妇引产开始至胎儿胎盘娩出时间明显缩短,产时出血量减少,清宫率降低。结论二者配伍用药效果显著,减轻产妇疼痛的时间,是一种使用方便、安全、有效、价格便宜的引产方法。

Objective To discuss the safety and efficacy of mifepristone combined with rivanol used in mild-tem preg- nancy induced labor. Methods The mild-tem pregnancy induced labor of healthy pregnant women were divided into two groups, control group： 100 mg of intramuscular injection of rivanol into amniotic cavity; experimental group： add mifepristone tablets 150 mg for oral. Results The time was significantly reduced of pregnant women with mifepristone rivanol odinopoeia note medicine the placenta to the fetus, the intrapartum haemorrhage amount was reduced, uterus clearaning rate was lower. Conclusion The compatibility of drug effect is remarkable, it can reduce the maternal pain time, it is a kind of easy to use, safe, effective and cheap method of induced labor.