45例老年人大细胞性贫血的病因分析

Etiological analysis of 45 elderly patients with macrocytic anemia

目的探讨老年人大细胞性贫血的病因。方法回顾性分析2011年1月～2012年1月在本院内科就诊的45例60岁以上的大细胞性贫血老年患者的床资料和实验室研究结果。结果 45例老年大细胞性贫血中,营养性巨幼细胞性贫血(MA)患者14例,占31.11%;骨髓增生异常综合征(MDS)患者11例,占24.44%;感染/风湿免疫性疾病(RID)患者10例,占22.22%。结论老年大细胞性贫血最常见的病因是营养性MA、MDS和RID。初诊时原因不明确的病例中MDS所占比例最高,应定期随访,密切监测,及早确诊。

Objective To investigate the etiology of elderly macrocytic anemia. Methods The clinical data and laboratory research results of 45 elderly patients with macrocytic anemia over the age of 60, who treated in medical depart- ment of our hospital from January 2011 to January 2012, were retrospectively analyzed. Results In 45 cases of elderly patients with macrocytic anemia, there were 14 cases of nutritional megaloblastic anemia aceounting for 31.11%, MDS patients for 11 cases accounting for 24.44%, and RID patients for 10 cases accounting for 22.22%. Conclusion The most common cause of senile macrocytic anemia is nutritional MA, MDS and RID. MDS accounted for the highest pro- portion in cases with initial unclear reason, so they should be followed up regularly, closely monitored and early diagnosed.