86株嗜麦芽窄食假单胞菌的标本分布及耐药性分析

86 Stenotrophomonas Maltophilia Specimen Distribution and Drug Resistance Analysis

目的:了解医院感染常见嗜麦芽窄食假单胞菌的耐药情况,为临床合理用药提供依据。方法:选择2011年1月-2012年12月我院收治患者临床标本分离出的86株嗜麦芽窄食假单胞菌,根据临床和实验室标准化研究所(CLSI)推荐的K-B法进行药敏试验。结果:嗜麦芽窄食假单胞菌主要来源于痰,占65.1%(56/86);其次是咽拭子,占14.0%(12/86)。药物敏感率最高是米诺环素86.0%,其次是复方新诺明和左氧氟沙星,药敏率分别为59.4%和40.7%,其他13种抗菌药物耐药率高达54.7%～100.0%。结论:嗜麦芽窄食假单胞菌已成为医院感染的主要致病菌之一,应加强耐药监测,根据药敏试验结果,合理规范使用抗菌药物。

Objective： To understanding the hospital infection Stenotrophomonas maltophilia resistance, provide the evident of the clinical use of drugs. Methods： From January 2011 to December 2012 all patients with clinical specimens in our hospital, among them we depart 86 Stenotrophomonas maltophilia, according to the K-B method recommended by the Clinical and Laboratory Standards Institute （CLSI） and then susceptibility trials, using WHONETS. 5 to Statistical analysis. Results. Stenotrophomonas maltophilia is mainly from sputum, 65. 1% （56/86）; followed by throat swab, 14.0% （12/86）. The highest rate of drug-sensitive is minocycline（86. 0%）, followed by eotrimoxazole, and levofloxacin, the susceptibility rates were 59. 4% and 40. 7%, the other 13 kinds of antimierobial drug resistance rates are as high as 54. 7 % to 100. 0%. Conclusion： Stenotrophomonas maltophilia has become one of the main pathogens of nosocomial infection, resistance surveillance should be strengthened, and reasonably regulate the use of antibiotics based on susceptibility testing results.