老年人原发性高血压与红细胞分布宽度的相关性

The correlation between essential hypertension and red blood cell distribution width in senile patients

目的:分析红细胞体积分布宽度(RDW)变异系数在老年人原发性高血压各级别间的差异,探讨老年人原发性高血压水平与RDW的相关性。方法:对191例首次确诊为1～3级原发性高血压的老年患者,分别记录收缩压、舒张压、RDW、血尿素氮、尿酸、血脂、同型半胱氨酸等进行分析;选择健康成人59名为对照组。采用直线相关性分析和多元线性逐步回归分析不同水平高血压与RDW变异系数的关系。结果:高血压各级别间RDW变异系数均差异无统计学意义(P>0.05);RDW变异系数与收缩压呈正相关关系。多元线性逐步回归分析表明收缩压是RDW变异系数的影响因素(β=0.351,P=0.002)。结论:RDW变异系数在老年人高血压各级别之间无显著性差异,RDW变异系数与收缩压呈正相关。

Objective：To analyze the variable coefficient difference of red blood cell distribution width （RDW） in different stage of elderly people essential hypertension and investigate the correlation between the level of essential hypertension and RDW. Methods ： The levels of systolic blood pressure, diastolic blood pressure, RDW, blood urea nitrogen, uric acid, blood lipid and homocysteine of 191 senile patients with stage 1,2 and 3 essential hypertension were measured and analysed. Fifty-nine healthy people acted as the control group. The correlation between different hypertension level and the variable coefficient of RDW was investigated using linear correlation analysis and multiple linear stepwise regression. Results：There was not statistical significance in the variable coefficient difference of RDW of different stage hypertension（ P 〉 0. 05 ）. The variable coefficient of RDW was positively related with systolic blood pressure. Multiple linear regression analysis showed that systolic blood pressure was a influencng factor of the variable coefficient of RDW（β = 0. 351,P = 0. 002）. Conclusions：The variable coefficient of RDW is not significant difference in different stage hypertens!on,which is positively related with systolic blood pressure.