强心康治疗慢性心力衰竭的疗效

Effect of Qiang Xin Kang on chronic heart failure

目的观察强心康制剂治疗慢性心力衰竭(CHF)患者的疗效。方法将符合纳入标准且BNP高于400 pg.mL-1的慢性心力衰竭患者随机分为试验组与对照组(各30例)。对照组给予常规西药规范化治疗;试验组加用强心康制剂(3片/次,每日3次),4周为1个疗程。比较2组用药前后BNP浓度及心功能变化。结果治疗后,2组的BNP均明显下降而左室射血分数(LVEF)均明显升高(均P<0.05),2组疗效比较,试验组优于对照组(P<0.05)。结论强心康可改善CHF患者的临床症状,提高患者生存质量。

Objective To observe the effect of Qiang Xin Kang in the treatment of chronic heart failure （ CHF）. Methods The patients with CHF whose BNP level higher than 400 pg · mL^-1 in plasma, divided into two groups which are the test group and the control group （both n = 30）. The two groups was given the conventional western medicine treat- ment. On thsi basis, patients in test group were give Qiang Xin Kang 3 tablets every time, three a day for 4 weeks. The plasma BNP level was determined and the change of heart function was investigated after treat- ment. Results The plasma BNP level in two groups were higher and then the LVEF were lower compared before and after treatment（ all P 〈 0. 05）. There were more effective in test group than the control group （P 〈 0. 05 ）. Conclusion Qiang Xin Kang could enhance clinical effect for CHF patient, and it improves patients＇ life quality.