新生儿败血症病原学及耐药性的临床分析

Clinical analysis of pathogens and drug resistance in neonatal septicemia

目的分析新生儿败血症病原菌的主要组成及其药物敏感情况和耐药性,为临床防治提供依据。方法统计2009年12月～2011年9月败血症新生儿血培养阳性的临床资料,分析药物耐药性和敏感资料。结果近2年新生儿败血症病原学的主要组成前4位依次为表皮葡萄球菌(20/45),大肠埃希氏菌(11/45),溶血性葡萄球菌(4/45),屎肠球菌(4/45),对临床常用抗生素的耐药性不断增强。结论葡萄球菌成为新生儿败血症的主要病原菌,耐药性强,在防治过程中必须高度重视。

Objective To investigate the pathogens and drug sensitivity of neonatal sepsis, for providing evidence for the prevention and the early treatment.Methods Statistics in December 2009, 12- 2011, 9. neonatal blood culture positive sepsis clinical data, analyze drug resistance and drug sensitive information Results The most common pathogens are Staphylococcus epidermidis, Escherichia coli, Hemolytic Staphylococcus and Feces Enterococcus. Conclusion Staphylococcus epidermidis, Escherichia coli are the main pathogens for neonatal sepsis. Possible strategies to improve the prognosis of neonatal sepsis include barrier nursing, strict aseptic manipulation and rational use of antibiotics.