摘要
铜是人体必不可少微量元素之一,铜缺乏和过量均会导致机体的异常,如Menkes和Wilson病。机体及细胞铜代谢的调控和铜稳态维护至关重要,涉及到铜的吸收、分储、排泄等过程。目前的研究对铜的代谢和稳态维护主要机制已经有比较全面的新的认识,对铜稳态研究正在逐渐完善和深入。
Copper plays an essential role in normal human physiology. Copper misbalance affects body dysfunction, such as Menkes＇ and Wilson＇ s disease. It is a key factor about the maintenance of the body and eel1 regulation of copper metabolism and copper homeostasis, related to the absorption, transport and removal of copper. Recent studies yielded new information on the function and regulation of human copper transporters, copper homeostasis and other metabolic pathways. The copper homeostasis regulation is emerging and perfecting.
出处
《安徽医药》
CAS
2013年第5期724-726,共3页
Anhui Medical and Pharmaceutical Journal
基金
国家自然科学基金(No 81072738
No 81173212)
关键词
铜稳态
铜代谢
铜转运蛋白
铜伴侣蛋白
copper homeostasis
copper metabolism
copper transport protein
copper chaperone protein
