布地奈德与地塞米松雾化吸入治疗急性喉炎临床疗效比较

Clinical efficacy comparison between budesonide and dexamethasone in the treatment of acute laryngitis

目的比较布地奈德与地塞米松雾化吸入治疗急性喉炎临床效果。方法将62例急性喉炎患者随机分为两组,A组30例给予地塞米松氧驱雾化吸入,B组32例给予布地奈德空气压缩雾化吸入,观察两组治疗效果。结果 A组治疗总有效率为73.33%,低于B组的96.88%(P<0.05);A组呼吸困难、喉鸣、咳嗽、声嘶消失时间及住院时间均长于B组的;A组不良反应发生率为33.33%,高于B组的6.25%(P<0.01)。结论布地奈德治疗小儿急性喉炎疗效优于地塞米松,可促进临床症状消除,患儿耐受性好,可作为急性喉炎的有效治疗药物。

Objective To compare the linical efficacy comparison between budesonide and dexamethasone in the treatment of acute laryngitis. Methods 62 cases of acute laryngitis patients were randomly assigned into two groups,30 cases in group A were treated by dexamethasone aerosol inhalation ,while 32 in group B were treated by budesonide compressed air inhalation. The effects of treatment were observed. Results Total effective rate of group A was 73.33 %, lower than in 96.88 % group B （ P 〈 0.05 ） ; breathing difficulties, cough, hoarseness disappearance time and hospital stay of group A were longer than those in group B （ P 〈 0. 05 ） ; Adverse reaction rate of group A was 33.33%, higher than in 6.25% group B. Conclusion Budesonide in the treatment of acute laryngitis is more effective than dexamethasone,which can promote the elimination of clinical symptoms in children with toleratanee,which can be used as effective drug for largngitis.