湖南省2009～2011年预防控制麻疹策略质量及效果评价

Evaluation on the Quality and Effect of Measles Prevention and Control in Hunan Province , 2009-2011

目的评价湖南省2009～2011年预防控制麻疹策略的质量及效果。方法通过综合分析湖南省含麻疹成分疫苗(Measles-containing Vaccine,MCV)的接种率,包括常规免疫接种率、麻疹减毒活疫苗补充免疫活动(Supplementary Immunization Activities,SIAs)和查漏补种接种率、疫苗效价监测、人群免疫成功率及抗体水平监测、麻疹监测系统资料,评价2009～2011年预防控制麻疹的效果。结果 2009～2011年,湖南省常规免疫MCV第一、第二剂报告接种率分别为99.52%、99.33%,SIAs报告接种率和调查接种率均>95%,疫苗效价均达到合格滴度,免疫成功率为89.38%,人群麻疹抗体平均阳性(≥1∶200)率78.28%,抗体几何平均滴度为1∶436。2011年发病率与2009年相比下降了97.46%,<8月龄及≥15岁的病例占全部病例的38.38%。结论湖南省预防控制麻疹措施效果显著,应继续加强麻疹监测,保持高质量的常规免疫,并针对重点人群开展免疫。

Objective To make an evaluation on the quality and effect of strategies fo measles prevention and control in Hunan province during 2009-2011. Methods To evaluate the effects of vaccination of measles-containing vaccine （MCV） in Hunan province during 2009-2011 by analyzing the coverage rate, including coverage of routine vaccination, SIAs, catch up vaccination, surveillance of vaccine efficiency, surveillance of antibody and data from the system of Measles surveillance. Results The inoculation rate of first dose and second dose MCV in routine immunization was 99.52% and 99.33% respectively. Both reported and investigated inoculation rate of SIAs are above 95%, all vaccine efficacy reached a qualified titre. The successful immunization rate was 89.38%, average positive rate of antiboday in population was 78.28%, geometric mean titer level was 1 ： 436, the incidence decreased 97.46%, and cases under 8 months or above 15 years of age accounted for 38.38%. Conclusion Measles prevention and control had got an outstanding effect in Hunan province. However, the surveillance for Meseales should be strengthened, high quality routine immunization must be maintained, and immunization campaign for high risk population should be conducted.