盐酸右美托咪定应用于小儿肠镜检查的效果与安全性

目的探讨盐酸右美托咪定应用于小儿肠镜检查的效果与安全性。方法将146例行肠镜检查的患儿随机分为观察组和对照组,对照组给予笑气镇痛,观察组给予盐酸右美托咪定镇痛。结果观察组总有效率大于对照组,但无显著性差异(2=0.507,P>0.05);观察组显效率显著大于对照组,差异有统计学意义(2=4.884,P<0.05);观察组不良反应发生率显著小于对照组,差异有统计学意义(2=4.755,P<0.05)。两组均未发生严重不良反应。结论盐酸右美托咪定应用于小儿肠镜检查,具有更高的有效性和安全性,值得临床考虑。

Objective To explore the clinical effectivity and safety of dexmedetomidine used for the enteroscopy of children. Methods 146 cases of child-patients were randomly divided into observational group and control group.The analgesia of nitrous oxide was given to control group, and analgesia of dexmedetomidine was given to observational group. Results The total effective rate of observational group was higher than that in control group, but no significant difference（X2=0.507,P〉0.05）; the efficiency effective rate was significantly higher than that in control group（X2=4.884,P〈0.05）; the side-reaction rate was significantly lower than that in control group（X2=4.755,P〈0.05）. There was no serious side-reaction happened in two groups. Conclusion Dexmedetomidine used for the enteroscopy of children owfi more higher effectivity and safety, so it deserved in clinical work.