卡前列素氨丁三醇与卡前列甲酯栓联合防治宫缩乏力性产后出血的临床观察

PREVENTION OF POSTPARTUM HEMORRHAGE BY CARBOPROST METHYLATE SUPPOSITORIES PLUS CARBOPROST TROMETHAMINE INJECTION IN HIGH RISK PREGNANT WOMEN

目的探讨卡前列素氨丁三醇与卡前列甲酯栓联合防治宫缩乏力性产后出血的效果。方法选取146例有剖宫产指征且有高危产后出血倾向的孕妇,随机分为卡前列甲酯栓组、卡前列素氨丁三醇组、卡前列素氨丁三醇+卡前列甲酯栓组,观察产后2h及24h出血量并进行比较。结果卡前列素氨丁三醇+卡前列甲酯栓组的2h及24h出血量比其他组的出血量要少。结论卡前列素氨丁三醇联合卡前列甲酯栓应用对预防和减少产后出血有良好的作用。

Objective To investigate the effect of Carboprost Tromethamine Injection plus Carboprost Methylate Suppositories on postpartum hemorrhage caused by uterine inertia. Methods A total of 146 pregnant women were randomly divided into 3 groups： a Carboprost Methylate Suppositories group, a Carboprost Tromethamine Injection group and a Carboprost Methylate Suppositories plus Carboprost Tromethamine Injection group. The amount of bleeding within 2 and 24 hours after the delivery were compared among the 3 groups. Results The amount of bleeding within 2 and 24 hours after the delivery in the Carboprost Methylate Suppositories plus Carboprost Tromethamine Injection group was significantly less than that in other groups. Conclusion Carboprost Methylate Suppositories plus Carboprost Tromethamine Injection is more effective and safer in the prevention and reduction of postpartum hemorrhage.