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自然杀伤细胞介导的固有免疫在慢性丙型肝炎病毒感染中的作用

Role of innate immunity mediated by natural killer cells in chronic hepatitis C virus infection
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摘要 丙型肝炎病毒(HCV)是导致慢性肝病的重要病原体。固有免疫在慢性丙型肝炎的致病机制中发挥了重要作用。自然杀伤(NK)细胞在肝脏中含量丰富,其在慢性HCV感染中介导的固有免疫反应是近年来研究的热点之一。文章对近年来在慢性HCV感染中NK细胞介导的抗病毒固有免疫反应方面的研究进行了综述。 Hepatitis C virus is the important pathogen of chronic liver diseases. The innate immunity plays a vital role in the pathogenesis of chronic hepatitis C. Natural killer cells, abundant in liver, mediate innate immunological response, which has been one of the hotspots in the researches in recent years. The research progress of innate immunological response mediated by natural killer cells in chronic hepatitis C infection is reviewed in this paper.
作者 方艳 Sandeepkumarkarn 张大志
机构地区 重庆医科大学附属第二医院感染病科
出处 《上海交通大学学报（医学版）》 CSCD 北大核心 2013年第5期681-684,共4页 Journal of Shanghai Jiao tong University:Medical Science
关键词 丙型肝炎病毒 自然杀伤细胞 固有免疫 hepatitis C virus natural killer cell innate immunity
分类号 R575.1 [医药卫生—消化系统] R392 [医药卫生—免疫学]
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参考文献25

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共引文献15

上海交通大学学报（医学版）
2013年 第5期

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