碳酸锂治疗甲状腺功能亢进症的利与弊

Advantages and disadvantages of lithium carbonate in the treatment of hyperthyroidisn~

碳酸锂作为精神性疾病的治疗药物在使用中发现可导致甲状腺功能减退、白细胞增多，因此被移作在一些特殊情况下甲状腺功能亢进症的治疗。当甲状腺功能亢进症患者对硫脲类抗甲状腺药物过敏、无效或合并白细胞减少时，碳酸锂可能是一种值得探索的治疗选择。但在使用中应注意监测血药浓度，选择较小剂量，避免药物的不良反应。

Lithium carbonate has been used as a psychiatric drug with some adverse effects such as hypothyroidism and leukocytosis. The adverse effects have been exploited for the treatment of hyperthyroid patients in particular conditions. It might be an alternative therapy for controlling hyperthyroidism in patients who can not tolerate or do not respond to thionamides or suffer from leukopenic condition. But it is important that monitoring serum lithium level, using smaller dose, and avoiding serious side-effects during the therapy of lithium carbonate should be carried out.