6种新型香豆素类衍生物的拉曼光谱研究

Raman spectra studies on six new coumarin derivatives

香豆素是一类应用很广泛的有机杂环化合物,具有抗HIV、抗癌、降压、抗心律失常等多种生物活性,具有很高的药用价值.本实验利用叔胺催化,合成了6种新型香豆素衍生物,采用激光显微拉曼光谱对其结构进行研究,归属各化合物拉曼谱峰,并探讨分子结构差异对拉曼光谱的影响.

The coumarins have been widely used as the organic heterocyclic compounds. It has very high medicine value duce to its biological activities in preventing HIV, preventing cancer, lowering blood pressure and preventing arrhythmia. In this study, six new derivatives of coumarin were synthesized by using the tertiary amine as catalyst, and then these coumarin derivatives were characterized by Raman spectra. Besides, the characteristic spectra of the compound were assigned and we discussed the effects of structure in different components on the Raman spectra.