肺大细胞癌54例临床分析

Analysis of large cell carcinoma of lung 54 cases

目的:本文旨在研究临床中肺大细胞癌(LCLC)的相关诊断以及通过总结外科手术治疗的一些经验,来进一步探讨其临床与病理特征,并对病患手术后的生存期进行了系统分析。方法回顾性的总结分析了冀中能源峰峰集团有限公司总医院自1982年2月至2010年4月间LCLC病患接受外科手术治疗的54例病患临床资料,其中:9例Ⅰa期,19例Ⅰb期,3例Ⅱa期,5例Ⅱb期,14例Ⅲa期,3例Ⅲb期,1例Ⅳ期。并对其生存率进行系统分析。结果 54例LCLC研究资料分析结果表明,1、3、5年生存率分别为74.1%、44.1%、31.6%。预后相对应的影响因素主要为TNM分期。结论 LCLC生存率低,预后相对较差、TNM分期也极大地影响着LCLC术后的生存率,而提高LCLC的早期发现率,及时进行手术是改善术后远期疗效的关键问题。

Objective To study the diagnosis of clinical lung large cell carcinoma（ LCLC ） and summarizes the experiences of surgical treatment, to further investigate the clinical and pathological features, and analyze the survival after surgery. Methods A retrospective summary analysis of our hospital from February 1982 to April 2010 ,the LCLC patients accepted surgical treatment of 54 cases of patients with clinical data,including：9 cases I a period,19 cases of stage I b,3 patients II a period of five cases of stage 11 b, 14 cases of stage HI a,3 cases of stage m b,and 1 cases of IV. And a systematic analysis of their survival. Results Totally 54 cases LCLC research data analysis showed that the 1 - ,3 - and 5 - year survival rates were 74. 1% ,44. 1% and 31.6%. The main factors affecting the prognosis corresponding TNM staging. Conclusions LCLC survival rate is low, the prognosis is relatively poor,TNM stage greatly influences the LCLC postoperative survival rate. The LCLC early detection rate, timely surgery is the key of improving the long - term efficacy of postoperative.