腹腔镜联合药物治疗中重度子宫内膜异位症并发不孕症疗效观察

Clinical observation of combined laparoscopic and medication in treatment of severe endometriosis concurrent infertility

目的探讨腹腔镜手术联合应用药物治疗中重度子宫内膜异位症并发不孕的临床疗效。方法回顾性分析许昌市公疗医院2009年6月至2011年6月收治的68例腹腔镜手术联合药物治疗的中重度子宫内膜异位合并不孕症患者诊疗资料,同单纯采用手术治疗的同期患者68例进行比较。两组患者在6、12、18、24个月复发率和妊娠率以及两组患者术后腹痛、性交痛发生率。结果观察组患者术后6、12、18、24个月复发率分别为8.82%、11.76%、17.65%、22.06%,明显低于对照组,组间比较差异具有统计学意义(P<0.05)。术后6、12、18、24个月妊娠率32.35%、39.71%、44.93%、57.35%,明显高于对照组,组间比较差异具有统计学意义(P<0.05)。结论在手术治疗的基础上联合应用药物治疗中重度子宫内膜异位症并发不孕症,可有效提高疗效,降低临床复发,提高妊娠率。

Objective To evaluate clinical efficacy of laparoscopic surgery combination medication in treatment of severe infertile women with endometriosis. Methods A retrospective analysis of our hospital from June 2009 to June 2011,68 patients were treated guessed laparoscopic surgery combined with drug therapy in severe endometriosis with infertility patient care information, with only using surgical treatment of the same period 68 patients to compare. Two groups of patients in the relapse rate of 6,12,18,24 months,and pregnancy,as well as two groups of patients with postoperative abdominal pain,the incidence of sexual pain. Results The recurrence rate in the observation group at 6, 12, 18,24 months after were lower than that of the control group, difference was statistically significant （ P 〈 0. 05 ）. The difference in the pregnancy rate between the two groups of 6,12,18,24 months after statistically significant （P 〈 0. 05 ）. Conclusions The surgical treatment on the basis of a joint application to severe endometriosis concurrent infertility medication, which can effectively improve the efficacy and reduce clinical recurrence in patients with early pregnancy ,worthy of promotion.