有创中心动脉压与外周动脉压和冠状动脉硬化的相关性

Correlation of invasive central arterial pressure with peripheral arterial pressure and coronary sclerosis

目的 研究外周无创及有创肱动脉血压、桡动脉血压与有创中心动脉压的一致性,探讨冠状动脉硬化程度与有创中心动脉压的相关性. 方法 选取我院行冠状动脉造影的患者共331例,测量其有创中心动脉压及有创、无创肱动脉压和桡动脉压,记录患者的动脉硬化程度；比较有创肱动脉压、桡动脉压以及无创肱动脉压、桡动脉压与有创中心动脉压的差异. 结果 有创与无创肱动脉压、桡动脉压收缩压均高于有创中心动脉收缩压,而四个外周动脉压舒张压均低于中心动脉舒张压,无创肱动脉压与有创中心动脉压数值更为接近,两者差异无统计学意义（P＞0.05）；随冠状动脉病变支数增多,有创中心动脉压收缩压也越高,舒张压反而降低,单支病变、2支病变和3支病变患者的有创中心动脉收缩压分别为（118.2±19.5）mm Hg、（124.9±19.7）mm Hg和（137.7±20.6）mmHg,舒张压分别为（86.8±8.4）mm Hg、（85.3±10.3）mm Hg和（83.1±9.4）mm Hg,差异有统计学意义（F=3.93、4.31,均P＜0.05）. 结论 无创肱动脉血压与有创中心动脉压数值最为接近,冠心病患者心脏病变程度与有创中心动脉压有明显相关性,无创肱动脉血压临床上可用于对早期心血管功能异常的检测.

Objective To study the consistency among non-invasive and invasive brachial artery pressure,radial artery pressure and invasive central arterial pressure,and to explore the correlation between the severe degree of coronary artery disease and invasive central aortic pressure.Methods A total of 331 patients who underwent coronary angiography in our hospital were selected.The invasive central aortic pressure,invasive and non-invasive brachial arterial pressure,radial artery pressure in all patients were measured.The severe degrees of atherosclerosis were recorded.The differences among invasive brachial arterial pressure and invasive radial artery pressure,non-invasive brachial artery pressure and non-radial artery pressure and invasive central aortic pressure were compared.Results The systolic pressure values measured in invasive and non-invasive brachial artery and radial artery were higher than that measured by central aortic pressure,while the diastolic pressure values measured in the four peripheral artery were lower than that measured in central aorta.The pressure values measured by non-invasive brachial artery pressure were more close to that measured by invasive central aortic pressure （P〉0.05）.The systolic pressure was increased and the diastolic pressure was reduced in central aortic pressure with the coronary vessel lession numbers increased.The values of systolic pressure in patients with single-vessel,double-vessel and triple-vessel lesions were （118.2± 19.5） mm Hg,（124.9 ± 19.7） mm Hg and （137.7 ± 20.6） mm Hg,respectively and the values of diastolic pressure were （86.8±8.4） mm Hg,（85.3± 10.3） mm Hg and （83.1± 9.4） mm Hg,respectively.There were significant differences in systolic and diastolic pressure values among patients with single-vessel lesions,double vessel lesions and triple-vessel lesions（F=3.93,4.31,both P〈 0.05）.Conclusions The blood pressure values measured by noninvasive brachial artery pressure are more close to that measured by invasive central aortic pressure.There is a significant correlation between the severe degree of coronary heart disease and invasive central aortic pressure.Non invasive brachial artery pressure can be used in the early detection of cardiovascular dysfunction.