细粒棘球绦虫抗原B的研究进展

Review on Antigen B of Echinococcus granulosus

细粒棘球绦虫抗原B(AgB)是血清学诊断棘球蚴病最重要的抗原,也是目前研究最多的抗原之一。深入研究抗原B对棘球蚴病的血清学诊断、流行病学研究、综合防控和疫苗的研究开发具有重要的意义。文章针对近年来关于抗原B的分子生物学特征、免疫学特性及在人和动物等中间宿主的血清学诊断方面的研究进展进行综述。

Antigen B（AgB） of Echinococcosis granulose was the most important antigen in the serological diagnosis of hydatid disease.Studies on antigen B of Echinococcosis granulose would promote the development of serological diagnosis agents,epidemiological studies and vaccines to prevent and control of hydatid disease.In this article,the research advances on molecular and immunological characteristics of antigen B and its potential applications on developing diagnosis methods and vaccines were reviewed.