基于Pubmed数据库的缺血性视神经病变文献计量分析

Bibliometric analysis on research of ischemic optic neuropathy from Pubmed database

目的了解缺血性视神经病变（ION）研究文献的研究热点。方法利用Pubmed数据库为数据源，对2000年1月至2012年7月所收录的ION相关文献进行统计分析，采用多元统计方法对高频主题词共现矩阵进行聚类分析，根据社会网络分析方法绘制可视化网络图谱。结果共检出ION相关文献1045篇。美国、英围、德国、法国和荷兰5个同家总发文量为748篇，占发文总数的71．58％。相关高频主题词共28个。聚类结果显示，当前的热点主要集中在4个领域，依次为：（1）手术源性及动脉炎性ION的研究；（2）ION的流行病学、病理学及诊断学研究；（3）I（）N的病理生理及治疗研究；（4）药物源性ION的研究。结论ION研究文献的研究热点主要集中在4个领域，可能为今后研究的发展重点和方向。

Objective To learn the hotspots of study in ischemic optic neuropathy （ION）. Methods I.iterature on ION published in January 2000 to July 2012 was identified in Pubmed database. MeSH terms that frequently appeared were identified and co-word analysis was carried out by duster analysis. Then a network was drawn using social network analysis. Results A total of 1045 papers were included. The United States, England, Germany, France and Netherlands together accounted for 71.53% （748） of the articles. There were 28 high frequency MeSH terms and hot topics clustered into four fields. The appearance frequency of MeSH showed that most research focused on： （1）postoperative or arteritie ION; （2） epidemiology, pathology and diagnosis of ION ; （3） pathophysiology and therapy of ION ; （4） chemically induced ION. Conclusion The international main research focus of ION includes four fields, which may provide reference or scholars both in scientific research and clinical research.