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前列腺癌治疗性DNA疫苗的研究进展

Research progress of therapeutic DNA vaccines for prostate cancer
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摘要 治疗性DNA疫苗是前列腺癌免疫治疗的新途径之一,本文主要介绍了以前列腺癌相关抗原PSA、PAP、PSMA、PSCA、STEAP等为靶点的DNA疫苗的研究现状,分析了DNA疫苗在前列腺癌免疫治疗领域的发展趋势及前景。 DNA vaccine is a new approach of immunotherapy for prostate cancer. This review provides a detailed look at the attributes and immunologic mechanisms of DNA vaccines encoding prostate cancer tissuespecific target antigens （PSA, PAP, PSMA, STEAP and PSCA） and their utility as well as potential prospects in prostate cancer immunotherapy.
作者 董金凯 高江平 王晓雄 于继云
机构地区 中国人民解放军总医院泌尿外科 军事医学科学院基础医学研究所
出处 《免疫学杂志》 CAS CSCD 北大核心 2013年第6期540-545,共6页 Immunological Journal
基金 国家自然科学基金项目(30840094)
关键词 前列腺癌 免疫治疗 DNA疫苗 肿瘤抗原 Prostate cancer Immunotherapy DNA vaccines Tumor antigens
分类号 R392 [医药卫生—免疫学]
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参考文献33

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二级参考文献12

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免疫学杂志
2013年 第6期

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