摘要
目的:研究合并桥本甲状腺炎对乳头状甲状腺癌颈淋巴结转移的影响。方法:回顾性分析3年间乳头状甲状腺癌的手术病例资料,筛选出符合研究要求样本224例。将患者分为观察组(乳头状甲状腺癌并存桥本甲状腺炎,n=45)和对照组(单纯乳头状甲状腺癌,n=179),比较两组间患者临床病理特征及颈淋巴结转移情况。结果:观察组女性患者比例明显多于对照组,中央区淋巴结清扫数明显高于对照组(均P<0.05),两组患者中央区及颈侧区淋巴结转移的平均值无统计学差异(均P>0.05)。多元回归分析显示,桥本甲状腺炎的存在与中央区及颈侧区淋巴结转移情况无明显关系(均P>0.05)。结论:乳头状甲状腺癌合并桥本氏甲状腺炎不是预测颈淋巴结发生转移的独立因素。
Objective: To investigate the influence of concomitant Hashimoto’s thyroiditis on papillary thyroid carcinoma(PTC) lymphatic metastasis.Methods: The data of PTC patients undergoing surgical treatment within a period of 3 years were retrospectively analyzed and 224 cases meeting inclusion criteria were selected.Patients were divided into observation group(PTC with Hashimoto’s thyroiditis,n=45) and control group(PTC only,n=179),and the clinicopathologic pro les and status of lymphatic metastasis of the two group were compared.Results: e proportion of female patients and number of dissected lymph nodes in the central compartment in observation group were significantly higher than those in control group(both P0.05).The differencesin average numbers of metastatic lymph nodes in the central compartment and lateral neck between the two groups had no statistical signiicance(both P0.05).Multiple regression analysis showed that concomitant Hashimoto’s thyroiditis was not associated with central and lateral neck metastasis in PTC patients(both P0.05).Conclusion: Concomitant Hashimoto’s thyroiditis in PTC patients is not an independent predictive factor for cervical metastasis.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2013年第5期580-584,共5页
China Journal of General Surgery
基金
黑龙江省自然科学基金资助项目(D201228)
哈尔滨医科大学附属第二医院青年基金资助项目(QN2012-07)
关键词
甲状腺肿瘤
癌
乳头状
桥本病
淋巴转移
yroid Neoplasms
Carcinoma
Papillary
Hashimoto Disease
Lymphatic Metastasis