摘要
目的:评价四物汤加味治疗原发性痛经的临床疗效。方法:以四物汤和痛经为检索词,计算机检索中国知网、万方数据库、中国生物医学文献数据库;搜索自1994年1月至2012年12月在国内公开发表的四物汤加味治疗原发性痛经的随机对照试验;采用Cochrance系统评价的方法评价纳入文献的质量,使用Rev Man 5.0版本对纳入的文献进行Meta分析。结果:共纳入13个随机对照试验,涉及1 531例患者,Meta分析结果显示四物汤加味治疗原发性痛经的治愈率及总有效率、复发率均优于对照组,其合并的OR值分别为:[OR=4.05,95%CI(3.18,5.16);OR=5.61,95%CI(3.98,7.90);OR=0.21,95%CI(0.12,0.35)]。结论:四物汤加味治疗原发性痛经与对照药相比,在治愈率及总有效率、复发率方面均有一定优势。
Objective: To assess the clinical efficacy of Siwu decoction modified for primary dysmenorrhea. Method: As Siwu decoction and dysmenorrhea for key terms, retrieved the randomized controlled trial of Siwu decoction modified for primary dysmenorrhea from CNKI, Wan fang data and Chinese biomedical Literature database from January 1994 to December 2012. Finally, evaluated the quality of incorporating literature with Cochrance system and analyzed them with the Meta analysis of Rev Man 5.0 version. Result: A total of 13 trials involving 1 531 patients were included. The meta-analyses showed that the cure rate, total efficiency and recurrence rate of Siwu decoction for primary dysmenorrhea were better than the control group. The combined OR values were OR=4.05,95%CI[3.18,5.16];OR=5.61,95%CI[3.98,7.90];OR=0.21,95%CI[0.12,0.35]. Conclusion: Compared with control group, Siwu decoction modified has some advantage in Cure rate, the total effective rate and recurrence rate for primary dysmenorrheal.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第11期325-329,共5页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
四物汤加味
原发性痛经
META分析
疗效评价
Siwu decoction modified
essential dysmenorrheal
Meta-analysis
efficacy evaluation