期刊文献+

体质指数与COPD患者生存预后关系的回顾性队列研究 被引量:15

A retrospective cohort study of relationship between body mass index and long-term survival in patients with chronic obstructive pulmonary disease
下载PDF
导出
摘要 目的:探讨体质指数(BMI)和慢性阻塞性肺疾病(COPD)长期生存率的关系。方法 :回顾性分析1436例COPD患者中符合条件的1 051例。死亡时间通过查询死亡登记处和民政部门确定,临床资料通过查阅病历获得。应用Cox比例风险回归模型评价全死因死亡率与BMI等因素的关系。结果:随访期间共有158例(15.0%)患者死亡,其年龄较大,病程较长,GOLD分级较高,BMI和FEV1较低,有合并症的患者较多,行长期家庭氧疗者较少。Cox多因素回归分析调整后,超重患者的死亡率较体重过低者降低了43%。生存分析证实超重组的患者生存率最高,体重过低组的生存率最低。结论:BMI对于评估COPD患者,尤其是急性加重期患者的长期预后具有一定的参考价值。 Objective To investigate the relationship between body mass index(BMI) and long-term survival in patients with chronic obstructive pulmonary disease(COPD).Methods 1051 patients with completed data among 1436 hospitalized patients due to COPD were retrospectively analyzed.The patient′s time of death was determined by querying death registries and civil affairs departments,and clinical datas were obtained from medical records.Cox model of proportional hazards was used to evaluate the relationship between all-cause mortality and BMI.Results 158 patients(15.0%) died in the period of follow-up.They were older and had a longer clinical course,ahigher GOLD grade,a lower BMI and FEV1,more patients with complications and less patients with LTOT.In an adjusted model,overweight patients had 43% less chance of death when compared to patients with low weight.The survival curves across BMI were statistical different.Highest survival was found for overweight patients and lowest survival was found for patients with low weight.Conclusion Body mass index has a certain reference value for the assessment of long-term prognosis of patients with COPD,especially for AECOPD patients.
作者 葛建军
出处 《实用医学杂志》 CAS 北大核心 2013年第10期1686-1688,共3页 The Journal of Practical Medicine
关键词 肺疾病 慢性阻塞性 体质指数 生存率 Pulmonary disease Chronic obstructive Body mass index Survival
  • 相关文献

参考文献5

  • 1Fang X, Wang X, Bai C. COPD in China: the burden and importance of proper management [J]. Chest, 2011, 139 (4) : 920-929.
  • 2曾伟光,曾艳芳,邱桂凤,荆维丽,杨茂祥,李有霞,李国帆,伍火志.慢性阻塞性肺疾病患者体质指数与深吸气量、用力肺活量的相关性研究[J].实用医学杂志,2011,27(16):2969-2971. 被引量:7
  • 3杨慧,张二明,郭伟安,张硕,时延伟,向平超.老年重度慢性阻塞性肺疾病的预后研究[J].中国呼吸与危重监护杂志,2012,11(3):213-217. 被引量:23
  • 4Lainscak M, Haehling S, Doehner W, et at. Body mass index and prognosis in patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease [J]. J Cachexia Sarcopenia Muscle, 2011, 2(2): 81-86.
  • 5van Wetering C R, Hoogendoorn M, Broekhuizen R, et al. Efficacy and costs of nutritional rehabilitation in muscle-wasted patients with chronic obstructive pulmonary disease in a community-based setting: a prespecified subgroup analysis of the INTERCOM trial [J]. J Am Med Dir Assoc, 2010, 11 (2) : 179-187.

二级参考文献20

  • 1向平超,姚震,程显声,张二明,张鑫,宋丽萍,鞠立新,丁彦,张莹.老年中度慢性阻塞性肺疾病长期预后随访研究[J].中华结核和呼吸杂志,2006,29(9):583-586. 被引量:14
  • 2慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8233
  • 3冉丕鑫,王辰,姚婉贞,陈萍,康健,黄绍光,陈宝元,王长征,倪殿涛,周玉民,刘升明,王小平,王大礼,吕嘉春,郑劲平,钟南山.体重指数与慢性阻塞性肺疾病及生活质量的关系[J].中华结核和呼吸杂志,2007,30(1):18-22. 被引量:82
  • 4李欣,赵建平,陈慧,朱丹,楼雅芳,涂军伟.稳定期慢性阻塞性肺疾病患者深吸气量测定的临床意义[J].中华结核和呼吸杂志,2007,30(1):23-26. 被引量:15
  • 5Decramer M, Rennard S, Troosters T, et al. COPD as a lung disease with systemic consequences-clinical impact, mechanisma, and potential for early intervention[J]. COPD, 2008,5 (4): 235 -256.
  • 6Agusti A G. systemic effects of chronic obstructive pulmonary disease [J]. Proc Am Thorac Soc, 2005,2(4):367-370.
  • 7Hallin R, Gudmundssonb G, Suppliulrik C, et al. Nutritional status and long-term mortality in hospitalised patients with chronic obstructive pulmonary disease(COPD) [J]. Respir Med, 2007,101 (9) : 1954-1960.
  • 8Newton M F, O'Donnell D E, Forkert L. Response of lung volumes to inhaled salbutamol in a large population of putients with severe hyperinflation [J]. Chest, 2002,121 (4) : 1042-1050.
  • 9Manriquez J, Diaz O, Borzone G, et al. Spirometric reversibility to salbutamol in obstructive pulmonary disease (COPD) Differential effects on FEV1 and on lung Volumes [J]. Rev Med Chil, 2004,132(7) : 787-793.
  • 10O'Donnell D E, Forkert L, Webb K A. Evaluation of bronchodilator responses in patients with "irreversible" emphysema [J]. Eur Respir J, 2001,18(6) :914-920.

共引文献28

同被引文献148

引证文献15

二级引证文献134

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部