口腔粘膜下纤维性变临床分型探讨

A Study on the Clinical Classification of Oral Submucous Fibrosis

目的 :为提高口腔粘膜下纤维性变 (OSF)的临床检出率和诊断率。方法 :对湖南省湘潭市 110 46人进行口腔普查 ,将检出的 335名OSF患者按不同临床表现分为弥漫型和局限型 ,其中具有OSF典型临床表现者为弥漫型 ,其它为局限型 ,并于 10年后复查了其中 72名患者。结果 :335名患者中弥漫型仅 13例 ,占 3 9% ,局限型 32 2例 ,占96 1%。复查显示 :在无适当治疗下 ,两型之间无相互转化。结论 :局限型OSF是湘潭地区OSF主要流行形式 ,是OSF的一种独立临床类型。

Objective: To increase the positive rate and sensitivity of the diagnosis for oral submucous fibrosis (OSF). Methods: A general oral survey of 11046 persons was carried out in Xiangtan, Hunan. According to Pindborg's diagnostic standard to epidemiological studies of OSF, 335 cases of OSF were found. The prevalence was 3%. According to different clinical manifestations, 335 cases of OSF were divided into two types: diffuse type and localized type. The cases with typical features of OSF, such as burning pain and discomfort, dryness of the mucosa, progressive inability to open the mouth and presence of palpable bands in the oral mucosa and so on, were in the diffuse type. Those with non typical features, only having presence of palpable bands in the oral mucosa, were in the localized type. 72 cases were followed up for ten years. Results: 335 cases of OSF were divided into two types. 13 cases (3 9%) were in the diffuse type, and 322 cases (96 1%) were in the localized type. Most of the OSF in this region belonged to the localized type. It was also discovered that without proper treatment, the subjects sticked to one type of OSF without changing from one type to another after ten years of follow up. Conclusion: Localized type of OSF is the major type of OSF in Xiangtan. It is an independent clinical type. To classify OSF, it is good for the clinicians to pay attention to non typical OSF. If the non typical OSF cases are taken into consideration, the prevalence of OSF will increase considerably.\;