锌制剂防治小儿急性腹泻98例临床分析

Clinical analysis of zinc preparation in the prevention and treatment of 98 children with acute diarrhea

目的分析探究锌制剂防治小儿急性腹泻的临床效果。方法选取本院收治的32例急性腹泻患儿,给予口服补液盐或静脉补液治疗,以及口服肠黏膜保护剂等综合治疗,作为对照组。另选98例急性腹泻患儿,作为观察组,观察组在对照组接受的治疗方案上加以口服葡萄糖酸锌口服液治疗。观察两组患儿大便频率、性状以及临床表现。结果观察组总有效率为92.86%,对照组总有效率为81.25%。观察组发热、呕吐、腹泻消退的时间远远小于对照组(P<0.05),观察组预后效果远远高于对照组(P<0.05)。结论锌制剂辅佐治疗小儿急性腹泻临床效果良好,有效治疗临床症状,帮助患儿早日康复,且无不良反应,值得临床推广使用。

Objective To explore the clinical effect of zinc preparation in the prevention and treatment of children with acute diarrhea. Methods Thirty two children with acute diarrhea admitted into our hospital and then provided with comprehensive therapies like oral rehydration salts, intravenous infusion, and oral intestinal mucosa protective a- gent were selected as control group. While in observation group, on the basis of treating the control group, oral liquid of zinc gluconate was additionally applied to treat 98 children with acute diarrhea. The frequency of defecation, stool property, and other clinical manifestations were observed in both groups. Results The total effective rate in the obser- vation group was 92.86%, while in the control group was 81.25%. The waning time of fever, vomiting, and abdominal diarrhea in the observation group were much shorter than those in the control group （P 〈 0.05）. The prognostic effect was superior to that in the control group （P 〈 0.05）. Conclusion Assistance of zinc preparation in the treatment of children with acute diarrhea obtains a favorable clinical effect, which effectively resolves the clinical symptoms and helps children patient recover as soon as possible. Without adverse reactions, it is worthy of extension in clinic.