难治性肾病综合征中西药结合治疗疗效观察

Effective observation on treating refractory nephrotic syndrome with Chinese traditional and Western medicine

目的探讨中西药结合治疗难治性肾病综合征的临床疗效。方法选取本院2012年1～10月收治的38例治疗案例进行随机分组,共分两组:西医治疗组(对照组)、中西医结合治疗组(观察组),对两组治疗效果和副反应情况进行比较。结果观察组总缓解率为68.4%,对照组总缓解率为47.4%,观察组临床疗效明显优于对照组,差异有统计学意义(P<0.05);观察组患者的蛋白尿及血脂、总胆固醇等指标均有显著改善(P<0.05);观察组副反应发生率明显低于对照组(P<0.05)。结论中西药结合治疗难治性肾病综合征疗效明显优于单纯西医治疗,且副反应少,值得在临床上应用和推广。

Objective To evaluate the clinical effect of the refractory nephrotic syndrome combined with Chinese tra- ditional and Western medicine. Methods Thirty eight cases of patients treated in our hospital were randomly divided into Chinese traditional and Western medicine care group and Western medicine group. Two groups were compared the clinical efficacy and adverse reactions. Results The total remission rate of observation group was 68.4%; The total re- mission rate of control group was 47.4%. The clinical effect of observation group was significantly better than the con- trol group; the difference was statistically significant （P 〈 0.05）. The observation group of patients with proteinuria and blood fat, total cholesterol etc. had significant improvement （P 〈 0.05）. The side effects of observation group was signif- icantly lower than the control group （P 〈 0.05）. Conclusion The clinical effect of Chinese traditional and Western medicine was significantly better than the Western medicine and less side effects ,worthy of promotion and application in clinical practice.