摘要
为探寻血液透析患者出现热原反应的原因，进行了微生物污染与消毒剂浓度调查。结果，消毒透析器所用过氧乙酸浓度低至０．０５％～０．１６％，贮罐中自来水、反渗水及透析器入口处透析液的细菌总数分别高达 １１ ２００ｃｆｕ／ｍｌ、 １５８０ｃｆｕ／ｍｌ与 １２５０ｃｆｕ／ｍｌ，透析液、反渗水细菌内毒素阳性率均为 １００％（ ２０／ ２０）。经确保过氧乙酸浓度≥０．３％，缩短消毒周期，改善液体过滤除菌设备，液体微生物检测均达标，未再出现热原反应。
In order to find out the cause of pyrogen reaction in patients receiving hemodialysis, microorganism contamination and disinfectant concentration were investigated. The results indicated that the concentration of peracetic acid used for disinfection of dialyzer was as low as 0.05% - 0. 16%, the total bacterial counts of tap water and reverse dialysis water in reservoir and the dialysate at the inlet of the dialyzer were as high as 11 200 cfu / ml, 1580 cfu / ml and 1250 cfu / ml respectively, and the positive rate of bacterial endotoxin both in dialysate and reverse dialysis water was 100% (20/ 20). After raising the concentration of paracetic acid to ≥ 0.3%, shortening the disinfection cycle and improving the equipment for fluid filtration and bacteria removal, microorganism examination of the fluid found to meet the sanitary standard and no pyrogen reaction occurred again.
出处
《中国消毒学杂志》
CAS
2000年第3期180-182,共3页
Chinese Journal of Disinfection
关键词
血液透析
透析液污染
细菌污染
热原反应消毒
investigation of contamination
contamination of dialysate bacterial contamination
pyrogen reaction
