4种药物疗法治疗充血性心力衰竭的临床观察

Clinical observation of quadruple medication in the treatment of congestive heart failure

目的 :观察在常规药物洋地黄、利尿剂治疗的基础上加用血管紧张素转换酶抑制剂 (ACEI)卡托普利及 β受体阻滞剂美托洛尔 4种药物治疗充血性心力衰竭 (CHF)患者的临床疗效。方法 :选择慢性 CHF患者 85例 ,根据治疗情况分成两组 :对照组 (39例 )常规给予洋地黄及利尿剂治疗 ;观察组 (46例 )在常规 2种药物治疗的基础上加用卡托普利及美托洛尔治疗。结果 :观察组与对照组的有效率分别为 84.8%、5 9.0 % (P <0 .0 5 ) ;即 4种药物疗法对心功能的改善明显优于常规 2种药物疗法。结论 :在常规药物洋地黄及利尿剂的基础上加用 ACEI及β受体阻滞剂治疗慢性

Objective:To observe the effect of quadruple medication in the treatment of congestive heart failure.Method:85 cases with congestive heart failure were divided into two groups. The patient of control group received routine treatment (Digitalis and diuretics). The observation groups (group 2) who had no severe bradycardia,Hypotersion and Ⅱ degree A V block were given captopril and metoprolol beside routine treatment.Result:The treatment efficiencies of the group 2 and group 1 were 84.8 % and 59.0 % (P< 0.05 ) respectively. The quadruple medication was clear better than routine treatment. Conclusion:In selected patients, the quadruple medication is the method of choice in the treatment of severe congestive heart failure.