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Apaf-1、Caspase-9及凋亡体调节的研究进展 被引量：6

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摘要 细胞凋亡（apoptosis），最早是由kerr等人于1972年首次提出，指生物体内绝大多数细胞在一定发育阶段由基因控制的、自主的、有序的死亡过程，它对于自身稳定的维持、组织的进化、器官的发育等起着重要的作用。细胞凋亡可能不是细胞死亡的唯一形式，但它却是目前由在结构、生化及基因水平已知非常详细的蛋白质构成的死亡通路唯一形式。细胞凋亡是一种古老的范式，可以追溯到最早的多细胞动物，但并不存在于植物、简单真核生物和微生物。细胞凋亡机制主要有外源性和内源性途径两种。
作者 孙军培 刘久华
机构地区 蚌埠医学院 蚌埠医学院附属连云港第二人民医院东院泌尿外科
出处 《中华全科医学》 2013年第7期1102-1104,共3页 Chinese Journal of General Practice
关键词 凋亡蛋白酶活化因子-1 细胞凋亡蛋白酶-9 细胞凋亡 凋亡复合体
分类号 R329.28 [医药卫生—人体解剖和组织胚胎学] R341 [医药卫生—基础医学]
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参考文献20

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共引文献6

同被引文献73

  • 1罗湘玉,罗卫民,郑雪松,张军.蓝藻素经Nrf 2/HO-1发挥对阿霉素心肌损伤大鼠的保护作用[J].中国生化药物杂志,2014,34(2):29-32. 被引量：1
  • 2陈如明,谢明星,高学运,张凯,单忠芳.复方中药制剂预防IBD的研究[J].中兽医医药杂志,1996,15(1):3-4. 被引量：18
  • 3侯水生,黄苇,刘五岳.我国养鸭业发展现状与前景分析[J].水禽世界,2007(1):37-38. 被引量：14
  • 4杨绍杰,孟金萍,屈祎,刘云波.细胞凋亡信号传导通路的研究进展[J].中国比较医学杂志,2007,17(5):297-301. 被引量：72
  • 5李超,伏圣博,刘华玲,马欣荣.细胞凋亡研究进展[J].世界科技研究与发展,2007,29(3):45-53. 被引量：75
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引证文献6

二级引证文献22

中华全科医学
2013年 第7期

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