正交试验法优选首明山胶囊的提取工艺

Study on extraction technology for Shoumingshan Capsules by orthogonal design

目的优化筛选首明山胶囊的提取工艺。方法采用正交试验法进行优选,以加水量、提取次数、提取时间为可变因素,以大黄素含量及干膏率为评价指标,筛选首明山胶囊的提取工艺条件。结果最佳提取工艺为以8倍量水提取3次,每次3 h。结论该提取工艺客观可行、稳定合理、重现性较好,得到了优选的首明山胶囊提取工艺。

Objective To establish the optimal extraction technology for Shoumingshan Capsules. Methods The or-thogonal test was employed for selecting the optimum of extraction technology. The investigation factors were the consumption of water,time and times of extraction. The extraction technology of Shoumingshan Capsules was screened by the transfer rate of emodin and ratio of dry extraction were observed. Results The best extraction condition was as follow：8 times of water, extracted for 3 times, each time was 3 h. Conclusion The above mentioned extraction technology was feasible, stable, rea-sonable and replieable, the optimized extraction process of Shoumingshan Capsules was obtained.