子宫内膜异位症癌抗原(CA125)检测及其临床意义

Detection of CA125 in endometriosis and its clinical significance

目的 :探讨子宫内膜异位症与CA12 5有无相关性 ,提高临床子宫内膜异位症诊断率和诊断最佳途径。方法 :用放射免疫测定法 (RIA)检测 79例子宫内膜异位症、70例子宫肌瘤、6 4例子宫颈癌 ;80名正常育龄女性为对照。结果 :子宫内膜异位症、子宫肌瘤、子宫颈癌、正常对照组阳性率分别是 79.75 %、8.5 7%、17.19%、0 .0 0 %。前者显著高于后三者 (P <0 .0 1)。结论 :CA12 5检测为临床诊断子宫内膜异位症开辟新的途径 ,且易推广。

Objective:To explore the relationship of the cancer antigen 125(CA125) with endometriosis.Methods:Serum CA125 was measured by RIA in patients with endometriosis,hysteromyoma and cervix cancer as well as normal controls.Results:The positive rates of serum CA125 detected in 79 patients with endometriosis,70 cases with hysteromyoma,64 cases with cervix cancer and 80 healthy normal subjects were 79.75 %,8.57%,17.19% and 0.00%,respectively.The positive rate of former was significantly higher than that of three latter groups.Conclusions:The results showed that there was an evident relationship between serum CA125 and endometriosis,and the detection of CA125 may be a new diagnostic method for endometriosis. [