药物洗脱球囊在血管介入治疗中的应用

Drug-eluting Balloon in Treatment of Vascular Intervention

近10年来,随着药物洗脱支架的出现,解决了临床上绝大多数病患的问题。然而,晚期血栓及支架内再狭窄的形成、缓释型药物涂层支架使内皮愈合时间延长、对小血管病变及分叉处病变的处理较局限以及手术后需服用双联抗血小板药物1年等方面的问题也严重制约着药物洗脱支架的临床获益度。近2年来,药物球囊的及时出现,成功克服了药物支架的这些缺陷。并且,值得一提的是,在应用药物球囊以后,病人只需短时间常规服用双联抗血小板药物,这也大大减轻了患者的经济负担。

Over the past 10 years, with the emergence of drug-eluting stents, the vast majority of patients with clinical problems have been solved. However, late stent thrombosis and restenosis, sustained-release drug-eluting stents to extend the endothelial healing time, the handling of more limited surgery to the small blood vessels （2.25 -2.75 mm） lesions and bifurcation lesions, and the requirement to take the double antiplatelet drugs for a year and other issues are seriously restricting the benefit of dmg-eluting stent clinical degree. Nearly two years, the timely emergence of dmg-eluting balloon, successfully overcome these shortcomings. And, it is worth mentioning that after the ap- plication of drug-eluting balloon, patients take only conventional dual antiplatelet drugs 1 - 3 months, which greatly reduce the financial bur- den of patients.