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思连康联合西替利嗪对慢性荨麻疹患儿血清IL-10、IFN-γ及疗效的影响 被引量:2

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摘要 目的探讨思连康联合西替利嗪对慢性荨麻疹患儿血清IL-10、IFN-γ及疗效的影响。方法将66例慢性荨麻疹患儿随机分为两组,观察组34例每日口服盐酸西替利嗪滴剂1mLQd,同时口服思连康片1gTid共2周;对照组32例每日口服盐酸西替利嗪滴剂,1mlQd共2周。两组于治疗前、治疗后1个月检测血清中IL-10、IFN-γ水平。结果观察组有效率88.2%,对照组有效率62.5%,两组有效率比较,差异有统计学意义(P<0.05);血清IL-10(pg/mL):观察组(2.97±1.25)明显低于对照组(4.38±1.04);血清IFN-γ(pg/mL):观察组(30.00±2.39)明显高于对照组(21.66±2.63)。两组比较,差异均有统计学意义(P<0.01)。结论慢性荨麻疹与机体免疫失衡有关,思连康与西替利嗪联合治疗可调节机体免疫失衡,提高疗效。
出处 《中外医疗》 2013年第12期135-136,共2页 China & Foreign Medical Treatment
基金 惠州市科技计划项目(2012Y109) 题目:益生菌对慢性荨麻疹患儿血清IL-10 IFN-Y及疗效影响
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