继发性脑室出血微创穿刺术后脑脊液细胞学变化的研究

The Study on Change of Cerebrospinal Fluid Cytology with Secondary Ventricular Hemorrhage after Microtrauma Evacuation of Hematoma

目的探讨继发性脑室出血患者行微创穿刺术后脑脊液细胞学的变化情况。方法对23例继发性脑室出血并行微创穿刺术患者进行腰穿脑脊液细胞学镜检分类。结果 3d以内脑脊液中可见大量新鲜的红细胞,中性粒细胞与红细胞之比（1：667）接近1：700,4~7d白细胞计数及中性粒细胞计数较前明显上升,7d以后白细胞计数及中性粒细胞计数开始下降,而淋巴细胞比值有所上升。结论脑脊液细胞学检查对于继发性脑室出血微创术后的病程判断、鉴别诊断具有重要临床价值。

Objective To study the change of cerebrospinal fluid cytology（CSFC） with secondary ventricular hemorrhage after mi- erotrauma evacuation of hematoma. Methods Lumbar puncture were performed in 23 patients with secondary ventricular hemor- rhage after microtrauma evacuation of hematoma, then CSFC were classified by microscope： Results A large number of erythro- cytes can be seen in the cerebrospinal fluid within three days, the ratio of neutrophils and erythrocytes approaches 1：700. White blood cell count and neutrophil count increase obviously in four to seven days. White blood cell count and neutrophil count re- duce significantly in seven to fourteen days, while the proportion of lymphocytes increases. Conclusion The examination of CSFC has important clinic value to the judgment of the course and the differential diagnosis of secondary ventricular hemorrhage.