摘要
目的探讨冠心病患者给予不同剂量的阿司匹林对血小板聚集功能的影响。方法选取2011年6月至2012年8月来我院进行治疗的冠心病患者156例,随机分为2组(n=78),所有的患者均口服阿司匹林,A组服用剂量为100mg,B组服用剂量为200mg,比较PAG在服药前及服药2周后的差异。结果与服用阿司匹林前比较,服药后两组患者的PAG(1)、PAG(5)、PAG(m)值均显著的降低(P<0.05),但是B组降低的幅度更大(P<0.05)。结论冠心病患者每天口服阿司匹林200mg能够更好的抑制血小板的聚集功能,其治疗剂量比较合理。
Objective To explore the different doses of aspirin on platelet aggregation in patients with coronary heart disease.Methods 156 cases with coronary heart disease were selected from June 2011 to August 2012 in our hospital,they were randomly divided into two groups,all the patients were given aspirin,the dose of Group A was 100mg,the dose of group B was 200mg,the difference of PAG between before the medication and medication 2 weeks after were comared.Results Compared with before use aspirin,PAG（1）,PAG（5）,PAG（m） after medication were significantly lower（P0.05）,group B decreased the amplitude greater（P0.05）.Conclusions Patients with coronary heart disease daily oral aspirin 200mg better able to inhibit platelet aggregation,its therapeutic dose is more reasonable.
出处
《中国医药指南》
2013年第9期29-30,共2页
Guide of China Medicine
关键词
冠心病
血小板聚集
阿司匹林
Coronary heart disease
Platelet aggregation
Aspirin
