摘要
目的观察阿昔洛韦、干扰素联合治疗小儿手足口病疗效观察。方法 96例患儿随机分为两组,对照组47例给予利巴韦林10mg/（kg d）静脉滴注,治疗组用注射用阿昔洛韦10mg/（kg d）静脉滴注基础上加用α-干扰素100万u＋生理盐水10mL喷喉q2h,疗程5~10d。结果治疗组退热及疱疹消退时间、进食时间均优于对照组,差异有统计学意义（P〈0.01）。治疗组总有效率98%,对照组总有效率85.1%,两组比较有统计学意义（P〈0.05）。结论阿昔洛韦、干扰素联合治疗小儿手足口病疗效确切,未见明显不良反应。
Objective To observe the acyclovir, interferon treatment of children with hand, foot and mouth disease patients. Methods 96 patients were randomly divided into two groups, control group 47 patients given intravenous ribavirin 10mg/（kg.d） the treatment group were injected intravenously with acyclovir 10mg/（kg.d） basis added with α-interferon 1 million u ＋ saline 10mL spray jets q2h, treatment 5-10d. Results The treatment group fever and herpes regression time, eating time were better than the control group, the difference was statistically significant （P〈0.01）. Efficiency of the treatment group was 97.9%, control group 89.4% total efficiency, the two groups was statistically significant （P〈0.05）. Conclusion Acyclovir, interferon treatment of children with hand, foot and mouth disease is effective, no significant adverse reactions.
出处
《中国医药指南》
2013年第9期415-416,共2页
Guide of China Medicine
关键词
阿昔洛韦
干扰素
联合治疗
小儿
手足口病
Aeyelovir
Interferon
Combination therapy
Children
Hand, foot and mouth disease
