医院感染中常见的几种革兰阴性杆菌的耐药情况分析

The Drug Resistance Analysis of the Most Common Gram Negative Bacilli in Hospital Infection

目的了解医院临床上分离出的容易发生医院感染的几种革兰阴性杆菌的耐药情况,从而为临床上经验性用药提供依据。方法选择我院自2010年8月至2012年8月医院临床科室中分离出的5761株常见的革兰阴性杆菌,采用K-B法检测对常用抗菌药物的敏感性进行回顾性分析。结果自2010年8月至2012年8月引起感染的致病菌主要以革兰阴性杆菌为主,且有逐年上升的趋势,2年中共检测到5761株,其中致病菌依次为铜绿假单胞菌10.69%、大肠埃希菌50.51%、鲍曼不动杆菌6.08%、肺炎克雷伯菌17.57%。结论医院中革兰阴性杆菌的耐药性已经日趋严重,根据临床药敏试验结果,加强抗菌药物的合理使用,可以控制医院内感染。

Objective To explore drug resistance of the most common gram negative bacillic from recent clinic, and provide the basis for clinical use of the drug. Mehtods From August 2010 to August 2012, 5761 strains of gram negative bacillic were isolated from all the clinical departments.The drug sensitivity of the common antibacterial agents were detected by K-B methods, Results From August 2010 to August 2012, the main pathogenic bacteria is gram negative bacillie, it tends to increase year by year. 5761 strains of gram negative bacillic were detected in 2 years.The pathogenic bacteria are pseudomonas aeruginosa（10.69%）, eschericbial coli （50.51%）, baumanii （6.08%） and klebsiella pneumoniae （17.57%）. Conclusion The drug resistance of gram negative bacillic could be gradually serious, we should strengthen the reasonable use of antimicrobial agents and control the hosiptal infection.