可测量人工晶状体波前像差的模型眼光路

An optical bench for measuring the wavefront aberrations of the intraocular lens

目的搭建模型眼光路，用以测量人工晶状体（IOL）的波前像差。方法实验研究。根据Hartmann-Shack原理，搭建了测量IOL像差的模型眼光路。光路含模型眼和辅助元件2部分。模型眼由焦距为28mm的相机镜头、置于生理盐水系统中的IOL（屈光度：＋10、＋15、＋20、＋25、＋30D）和电荷耦合照相机（CCD）组成。辅助元件包括光源、滤波片（覆盖波长：436．0、486．0、525．0、546．1、589．0、660．0、710．0nm）、微透镜阵列、焦距为100mm的消色差透镜。采用自行编写的程序（Matlab软件，v7．1）分析CCD接收的图像，获得IOL的Zernik值、调制传递函数和点扩散函数等表示像差的参数。结果本研究搭建的模型眼光路，通过改变光路中的滤波片或IOL，可测量不同屈光度的IOL在不同波长入射光的模型眼光路中的波前像差，尤其是球差和总高阶像差。结论搭建模型眼光路用于IOL波前像差的测量，实现了客观评价IOL成像质量的目的。

Objective To construct an optical bench that can measure the wavefront aberrations of the intraocular lenses （IOLs）. Methods This was an experimental study. An optical path was constructed to measure the wavefront aberrations of IOLs based on the Hartmann-Shack principle. The optical bench was composed of 2 parts： an eye model and optical components. The eye model was a combination of a spherical photographic lens with a 28 mm focal length, a water cell containing the IOLs （diopters： ＋10, ＋15, ＋20, ＋25, ＋30 D） and a charge-coupled device （CCD）. The optical components were composed of a light source, filters （peak wavelengths： 436.0, 486.0, 525.0, 546.1, 589.0, 660.0, 710.0 nm）, a micro-lens array with a 15 mm focal length and an achromatic doublet lens with a 100 mm focal length. The images received by the CCD were analyzed with Matlab software. IOL Zemik polynomials and wavefront aberration parameters such as modulation transfer function and point spread function were also obtained. Results By changing the filters or IOLs on the optical bench, the wavefront aberrations of each IOL were measured at different wavelengths of 436.0-710.0 nm, so the spherical aberrations and higher order aberrations of the IOLs could be compared. Conclusion Wavefront aberrations of IOLs can be measured in this optical path, therefore the optical properties of the IOLs can be evaluated objectively.