摘要
耳由于解剖位置深在、结构精细复杂和功能的重要性,对耳科疾病发病机制、诊断和治疗的研究仍然是一个难点。病毒由于无处不在,其致病性往往受到忽视,近年研究者们借助先进的检查技术发现病因不明的特发性耳部疾病与病毒感染相关,特别是疱疹病毒属,与中耳炎、耳聋和前庭疾病等关系密切,对其致病机制和治疗的研究也成为热点。
The association of viral infection to ear disease has triggered a great deal of interests.In the present paper,we provide a critical review of the viral hypothesis of ear diseases.Detection of viral antigen and antibody or RNA and DNA in the patients＇ serum,endolymphatic fluid or surgical pathology specimens reveals that virus may have relevance to certain kinds of ear diseases,such as Meniere＇s disease,idiopathic sudden sensorineural hearing loss,otosclerosis,Bell＇s palsy and otitis media.The most appealing is the herpesvirus,which can cause latent infection in the neurons,and its reactivation may be the mechanism of recurrent attacks of ear diseases.Currently,antiviral drug treatment plus supportive therapy are the most effective managements dealing with viral infection.Although antiviral vaccine will become a promising preventive strategy in the future.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2013年第10期500-504,共5页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
病毒感染
耳科疾病
临床检测
治疗
viral infection
ear disease
clinical detection
therapy
