苗族和布依族女性血清神经内分泌激素水平及影响因素比较研究

Comparative study on the blood serum neuroendocrine hormone level and risk factors between Miao and Buyi race women

目的:探讨苗族和布依族女性血清神经内分泌激素水平,并比较影响两民族神经内分泌激素水平差异的因素。方法:2011年3月～2012年6月在贵州省黔南州中医医院治未病中心进行健康体检女性人群共359例,按民族将其分为苗族组(173例)和布依族组(186例)。采用化学发光免疫法测定两组研究对象血清中催乳素(PRL)、促黄体生成素(LH)、睾酮(TST)、尿促卵泡素(TSH)及多巴胺(DA)水平。结果:苗族组女性血清TST水平明显高于布依族组,而LH、TSH及DA水平则低于布依族组,差异有统计学意义(P<0.05)。根据年龄将两民族女性分为4个年龄段,两组20～29岁、30～39岁、40～49岁、50～59岁年龄段女性LH、TST、TSH及DA水平比较差异有统计学意义(P<0.05);两组20～29岁和30～39岁年龄段女性PRL水平比较差异无统计学意义(P﹥0.05);两组40～49岁和50～59岁年龄段女性PRL水平比较差异有统计学意义(P<0.05)。结论:苗族女性血清神经内分泌激素水平与布依族女性存在民族差异。

Objective： To investigate the blood serum neuroendocrine hormone level and analyze the difference and the risk factors for Miao and Buyi race women. Methods： 359 women were taken as research object which were divided into two groups according to their races, ineluding 173 Miao persons and 186 Buyi persons. All subjects had no genital system diseases and no hormonal medication history within the 3 months. Prolactin （PRL）, luteinizing hormone （LH）, testosterone （TST）, thyroid stimulating hormone （TSH） and dopamine （DA） contents in the blood sermn were tested by chemiluminescence immunization. Results： ①LH, FSH and DA levels in the Miao race woman group was significantly lower than those of the Buyi race women group, but TST level was higher （ P 〈 0. 05 ） .②The two races women were divided into 4 groups according to the age, the differences in TST, TSH and DA levels of the Miao race women of 20 -29 ages, 30 - 39 ages, 40 - 49 ages, 50 - 59 ages groups and the Buyi race women group respectively were significant （ P 〈 0. 05 ） . while differences in PRL between the Miao race women groups of the 20 - 29 ages and 30 - 39 ages and Buyi race women groups were not significant （ P 〉 0.05 ） . Conclusion： There are national differences in the blood serum neuroendocrine hormone levels between Miao and Buyi persons.