年轻妇科肿瘤患者化疗后骨密度变化50例临床分析

Clinical analysis of bone mineral density changes of 50 young patients with gynecological tumor after chemotherapy

目的:研究分析妇科肿瘤年轻患者化疗后骨密度的变化,为临床工作提供参考。方法:以2009年1月～2012年8月该院收治的宫颈癌患者50例为实验组,患者均采用手术治疗且在手术后进行化疗;以同期在该院进行健康体检的50例女性作为对照组。观察实验组化疗后的骨密度变化,并与对照组进行比较。结果:实验组患者化疗前与对照组骨密度比较,P>0.05;实验组患者化疗后骨密度降低,与化疗前比较P<0.05,与对照组比较P<0.05,差异有统计学意义。结论:在妇科肿瘤年轻患者化疗期间,其骨密度有明显降低,需要医生引起高度重视,使用多种方法提高患者骨密度。

Objective： To analyze the bone mineral density （BMD） in the gynecologic oncology young patients after chemotherapy and give a reference for clinical work. Methods： From January 2009 to August 2012, 50 cases of cervical cancer patients were selected into experimental group and treated by surgery and chemotherapy after surgery. At the same period 50 cases of women were selected into control group. BMD change in experimental group was observed and compared with that of control group. Results ： There was no difference in BMD between the experimental group before chemotherapy and the control group （P 〉 0. 05）. BMD was reduced after chemotherapy in the experi- ruental group, compared with chemotherapy before （ P 〈 0. 05）, compared to the control group （P 〈 0. 05） , the difference was statistically significance. Conclusion： During chemotherapy of gynecologic oncology young patients, BMD has been decreased significantly, doctors are required to attach great importance to use a variety of methods to improve BMD.