摘要
目的观察补肾柔肝方治疗卵巢早衰(POF)的临床疗效。方法将80例卵巢早衰患者随机分为2组,治疗组50例予补肾柔肝方治疗,对照组30例予常规西药治疗,2组疗程均为6个月。观察治疗前后血清卵泡刺激素(FSH)、雌二醇(E2)水平和T淋巴细胞亚群CD4、CD8、CD4/CD8的变化,同时观察主要症状的改善情况。结果 2组治疗后FSH水平均较本组治疗前降低(P<0.05),E2水平均较本组治疗前升高(P<0.05)。2组治疗后FSH、E2水平比较差异均无统计学意义(P>0.05)。治疗组治疗后CD4细胞较本组治疗前、对照组治疗后均增加(P<0.05),CD8细胞减少(P<0.05),CD4/CD8提高(P<0.05)。2组治疗后主要症状改善率比较差异无统计学意义(P>0.05)。结论补肾柔肝方能显著改善POF患者的生活质量,恢复卵巢功能,同时提高机体免疫力,安全有效。
Objective To investigate the effect of premature ovarian failure treated by Bushen Rougan prescription.Methods 80 cases of premature ovarian failure patients were randomly divided into two groups.The treatment group of 50 cases was treated by Bushen Rougan prescription,control group of 30 patients was treated with conventional western medicine,and a course is 6 months.The levels of serum follicle stimulating hormone(FSH) and estradiol(E2) before and after treatment and changes of T lymphocyte subsets CD4 and CD8,while the improvement of the main symptoms was observed.Results The level of FSH after treatment was decreased as compared with that before treatment in two groups(P〈0.05).The level of E2 was increased(P〈0.05).There was no difference between two groups on the level of FSH and E2 after treatment(P〈0.05).CD4 after treatment in treatment group was increased as compared with that before treatment in treatment group and after treatment in control group(P〈0.05).CD8 was decreased(P〈0.05),CD4/CD8 was increased(P〈0.05).There was no difference between two groups on the improvement of the main symptoms after treatment(P〈0.05).Conclusion Bushen Rougan prescription can significantly improve the quality of life of patients with premature ovarian failure,restore and improve ovarian function,at the same time improve the immune capacity,it is safe and effective.
出处
《河北中医》
2013年第3期339-341,共3页
Hebei Journal of Traditional Chinese Medicine
关键词
卵巢功能早衰
中药疗法
Premature ovarian failure
Traditional Chinese medicine therapy