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绵地花菌(Albatrellus ovinus)中的grifolin及其衍生物 被引量：4

Grifolin Derivatives from the Basidiomycete Albatrellus ovinus
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摘要 本文对高等真菌绵地花(Albatrellus ovinus)进行了化学成分的研究。利用各种柱色谱方法(包括正相硅胶、反相硅胶、Sephadex LH-20凝胶色谱、中压液相色谱、半制备HPLC等),分离得到grifolin及其它的5个衍生物。分别为grifolin(1)、neogrifolin(2)、grifolinone A(3)、grifolinone C(4)、confluentin(5)和4-O-methylgrifolic acid(6)。这些化合物的结构通过波谱学方法以及与文献数据对照进行确定。化合物3～6为首次从该种高等真菌中分离得到。化合物4为一个真菌色素,它是一个由一分子的grifolin和一分子苯醌化的grifolin以头对头的方式聚合而成的二聚体。 This paper reported the chemical constituents from the fruiting bodies of the higher fungus Albatrellus ovinus collected from Anhui province,China.Grifolin and five grifolin derivatives were isolated by silica gel,Sephadex LH-20 column chromatography,and HPLC.Their structures were identified as grifolin（1）,neogrifolin（2）,grifolinone A（3）,grifolinone C（4）,confluentin（5）,and 4-O-methylgrifolic acid（6）,on basis of spectroscopic analysis and comparison with literatures.
作者 陆晓民 刘良燕 李正辉 董泽军 刘吉开
机构地区 安徽科技学院 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室 中科院研究生院
出处 《天然产物研究与开发》 CAS CSCD 北大核心 2013年第5期617-619,共3页 Natural Product Research and Development
基金 安徽科技学院生物学重点建设学科项目(AKXK20102-1)
关键词 高等真菌 绵地花菌 化学成分 grifolin衍生物 higher fungus Albatrellus ovinus chemical constituents grifolin derivatives
分类号 R284.2 [医药卫生—中药学]
  • 相关文献

参考文献11

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  • 2Ding ZH, Dong ZJ, Liu JK. Albaconol, a novel prenylated resorcinol ( = benzene-l, 3-diol) from basidiomycetes Albatrellus confluens. Helv Chim Acta,2001,84 :259-262.
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共引文献6

同被引文献45

  • 1刘明华,肖顺汉,秦大莲,章卓,卿晨,张雁丽.地花菌提取物Albaconol的抗肿瘤活性研究[J].中药药理与临床,2005,21(1):14-16. 被引量：6
  • 2谢学明,钟远声,李熙灿,黄海波,刘晓玲,麦惠环.22种华南地产药材的抗氧化活性研究[J].中药药理与临床,2006,22(1):48-50. 被引量：35
  • 3郑焕娣,刘培贵.地花菌属的研究概况和进展[J].微生物学通报,2006,33(6):104-107. 被引量：7
  • 4Luo D Q, Shao H J, Zhu H J, et al. Activity in vitro and in vivo against plant pathogenic fungi of grifolin isolated from the basidiomycetes AlbatreUus dispansus [J]. Z Naturforsch C,2005, 60(1-2) :50-56.
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引证文献4

二级引证文献5

天然产物研究与开发
2013年 第5期

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